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SMILES: O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1cc(=O)c2ccccc2o1

InChI Key: InChIKey=FVCAEWCYJLYCAB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181419   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50181419
PNG
(CHEMBL370866 | N-(3-{2,3-dihydrospiro[indene-1,4'-...)
Show SMILES O=C(NCCCN1CCC2(CCc3ccccc23)CC1)c1cc(=O)c2ccccc2o1
Show InChI InChI=1S/C26H28N2O3/c29-22-18-24(31-23-9-4-2-7-20(22)23)25(30)27-14-5-15-28-16-12-26(13-17-28)11-10-19-6-1-3-8-21(19)26/h1-4,6-9,18H,5,10-17H2,(H,27,30)
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n/an/a>1.00E+3n/an/an/an/an/an/a



Banyu Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells

J Med Chem 49: 847-9 (2006)


Article DOI: 10.1021/jm0509851
BindingDB Entry DOI: 10.7270/Q2DJ5F78
More data for this
Ligand-Target Pair