BDBM50181443 3-(2-aminoethyl)-2-chloro-4-hydroxy-5-(3-phenoxyphenyl)thieno[2,3-b]pyridin-6(7H)-one::CHEMBL202126

SMILES: NCCc1c(Cl)sc2[nH]c(=O)c(c(O)c12)-c1cccc(Oc2ccccc2)c1

InChI Key: InChIKey=YIMSHHMJWBMJCZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50181443 (3-(2-aminoethyl)-2-chloro-4-hydroxy-5-(3-phenoxyph...) Show SMILES NCCc1c(Cl)sc2[nH]c(=O)c(c(O)c12)-c1cccc(Oc2ccccc2)c1 Show InChI InChI=1S/C21H17ClN2O3S/c22-19-15(9-10-23)17-18(25)16(20(26)24-21(17)28-19)12-5-4-8-14(11-12)27-13-6-2-1-3-7-13/h1-8,11H,9-10,23H2,(H2,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membrane				J Med Chem 49: 864-71 (2006) Article DOI: 10.1021/jm0503493 BindingDB Entry DOI: 10.7270/Q2513XS4
					More data for this Ligand-Target Pair