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BDBM50181458 5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazolidine-2,4-dione::CHEMBL201383

SMILES: Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=LOELFYANKAFOQY-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181458   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50181458
PNG
(5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...)
Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
905n/an/an/an/an/an/an/an/a



Universit£ catholique de Louvain

Curated by ChEMBL


Assay Description
Displacement of [3H]SR141716A from human CB1 receptor


J Med Chem 49: 872-82 (2006)


Article DOI: 10.1021/jm050484f
BindingDB Entry DOI: 10.7270/Q28916NK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50181458
PNG
(5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...)
Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H
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PubMed
1.74E+3n/an/an/an/an/an/an/an/a



Universit£ catholique de Louvain

Curated by ChEMBL


Assay Description
Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum


J Med Chem 49: 872-82 (2006)


Article DOI: 10.1021/jm050484f
BindingDB Entry DOI: 10.7270/Q28916NK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50181458
PNG
(5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...)
Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H
PDB

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n/an/an/an/a 1.23E+3n/an/an/an/a



Universit£ catholique de Louvain

Curated by ChEMBL


Assay Description
Potency at human CB1 receptor in a [35S]GTP-gamma-S functional assay


J Med Chem 49: 872-82 (2006)


Article DOI: 10.1021/jm050484f
BindingDB Entry DOI: 10.7270/Q28916NK
More data for this
Ligand-Target Pair