null

SMILES: Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1

InChI Key: InChIKey=LOELFYANKAFOQY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50181458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50181458 (5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...) Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	905	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ catholique de Louvain Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from human CB1 receptor				J Med Chem 49: 872-82 (2006) Article DOI: 10.1021/jm050484f BindingDB Entry DOI: 10.7270/Q28916NK
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50181458 (5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...) Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ catholique de Louvain Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum				J Med Chem 49: 872-82 (2006) Article DOI: 10.1021/jm050484f BindingDB Entry DOI: 10.7270/Q28916NK
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50181458 (5-(4-bromophenyl)-1,3-bis(4-chlorophenyl)imidazoli...) Show SMILES Oc1c(-c2ccc(Br)cc2)n(-c2ccc(Cl)cc2)c(=O)n1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H13BrCl2N2O2/c22-14-3-1-13(2-4-14)19-20(27)26(18-11-7-16(24)8-12-18)21(28)25(19)17-9-5-15(23)6-10-17/h1-12,27H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a
Universit£ catholique de Louvain Curated by ChEMBL					Assay Description Potency at human CB1 receptor in a [35S]GTP-gamma-S functional assay				J Med Chem 49: 872-82 (2006) Article DOI: 10.1021/jm050484f BindingDB Entry DOI: 10.7270/Q28916NK
					More data for this Ligand-Target Pair