new BindingDB logo
myBDB logout

BDBM50181469 1,3-bis(3-chlorophenyl)-5-phenylimidazolidine-2,4-dione::CHEMBL201291

SMILES: Oc1c(-c2ccccc2)n(-c2cccc(Cl)c2)c(=O)n1-c1cccc(Cl)c1

InChI Key: InChIKey=NNJRMFRWWSAFBM-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181469   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50181469
PNG
(1,3-bis(3-chlorophenyl)-5-phenylimidazolidine-2,4-...)
Show SMILES Oc1c(-c2ccccc2)n(-c2cccc(Cl)c2)c(=O)n1-c1cccc(Cl)c1
Show InChI InChI=1S/C21H14Cl2N2O2/c22-15-8-4-10-17(12-15)24-19(14-6-2-1-3-7-14)20(26)25(21(24)27)18-11-5-9-16(23)13-18/h1-13,26H
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.11E+3n/an/an/an/an/an/an/an/a



Universit£ catholique de Louvain

Curated by ChEMBL


Assay Description
Displacement of [3H]SR141716A from human CB1 receptor


J Med Chem 49: 872-82 (2006)


Article DOI: 10.1021/jm050484f
BindingDB Entry DOI: 10.7270/Q28916NK
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50181469
PNG
(1,3-bis(3-chlorophenyl)-5-phenylimidazolidine-2,4-...)
Show SMILES Oc1c(-c2ccccc2)n(-c2cccc(Cl)c2)c(=O)n1-c1cccc(Cl)c1
Show InChI InChI=1S/C21H14Cl2N2O2/c22-15-8-4-10-17(12-15)24-19(14-6-2-1-3-7-14)20(26)25(21(24)27)18-11-5-9-16(23)13-18/h1-13,26H
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 936n/an/an/an/a



Universit£ catholique de Louvain

Curated by ChEMBL


Assay Description
Potency at human CB1 receptor in a [35S]GTP-gamma-S functional assay


J Med Chem 49: 872-82 (2006)


Article DOI: 10.1021/jm050484f
BindingDB Entry DOI: 10.7270/Q28916NK
More data for this
Ligand-Target Pair