BDBM50181524 CHEMBL3819161
SMILES: COc1ccc(CSc2nc3c(nc(N)[nH]c3=O)[nH]2)c(F)c1
InChI Key: InChIKey=BEPYKLJEDUOZIK-UHFFFAOYSA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (Escherichia coli (strain K12)) | BDBM50181524 (CHEMBL3819161) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a |
Monash University Curated by ChEMBL | Assay Description Binding affinity to biotinylated Escherichia coli HPPK expressed in Escherichia coli BL21 (DE3) in presence of 1 mM ATP by SPR assay | J Med Chem 59: 5248-63 (2016) BindingDB Entry DOI: 10.7270/Q2057HWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase (Staphylococcus aureus) | BDBM50181524 (CHEMBL3819161) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
Monash University Curated by ChEMBL | Assay Description Binding affinity to biotinylated Staphylococcus aureus HPPK in presence of 1 mM ATP by SPR assay | J Med Chem 59: 5248-63 (2016) BindingDB Entry DOI: 10.7270/Q2057HWV | |||||||||||
More data for this Ligand-Target Pair |