BDBM50181567 4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-6-yloxy]acetonitrile::CHEMBL201690

SMILES: CC(C)CCn1c2ccc(OCC#N)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=QFXIOPUUUDMJAN-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181567 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC#N)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:20| Show InChI InChI=1S/C23H22N4O5S/c1-14(2)9-11-27-18-8-7-15(32-12-10-24)13-16(18)21(28)20(23(27)29)22-25-17-5-3-4-6-19(17)33(30,31)26-22/h3-8,13-14,28H,9,11-12H2,1-2H3,(H,25,26)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	298	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of HCV RNA replication in Huh7 cells				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181567 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC#N)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:20| Show InChI InChI=1S/C23H22N4O5S/c1-14(2)9-11-27-18-8-7-15(32-12-10-24)13-16(18)21(28)20(23(27)29)22-25-17-5-3-4-6-19(17)33(30,31)26-22/h3-8,13-14,28H,9,11-12H2,1-2H3,(H,25,26)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair