null

SMILES: CC(C)CCn1c2ccc(OCC(N)=O)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=XCBRQLUBWBEIBB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181584 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC(N)=O)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:21| Show InChI InChI=1S/C23H24N4O6S/c1-13(2)9-10-27-17-8-7-14(33-12-19(24)28)11-15(17)21(29)20(23(27)30)22-25-16-5-3-4-6-18(16)34(31,32)26-22/h3-8,11,13,29H,9-10,12H2,1-2H3,(H2,24,28)(H,25,26)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	511	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of HCV RNA replication in Huh7 cells				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181584 (4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-...) Show SMILES CC(C)CCn1c2ccc(OCC(N)=O)cc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:21| Show InChI InChI=1S/C23H24N4O6S/c1-13(2)9-10-27-17-8-7-14(33-12-19(24)28)11-15(17)21(29)20(23(27)30)22-25-16-5-3-4-6-18(16)34(31,32)26-22/h3-8,11,13,29H,9-10,12H2,1-2H3,(H2,24,28)(H,25,26)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair