BDBM50181596 3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(2-methylsulfanylethyl)-1H-quinolin-2-one::CHEMBL201456

SMILES: CSCCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=GWUKJQSSVUJDMV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181596 (3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...) Show SMILES CSCCn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:15| Show InChI InChI=1S/C19H17N3O4S2/c1-27-11-10-22-14-8-4-2-6-12(14)17(23)16(19(22)24)18-20-13-7-3-5-9-15(13)28(25,26)21-18/h2-9,23H,10-11H2,1H3,(H,20,21)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair