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SMILES: Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2ccccc2)c2ccccc12

InChI Key: InChIKey=TZGXXSCQCVEASE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181605   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181605
PNG
(1-benzyl-3-(1,1-dioxo-1,2-dihydro-benzo[1,2,4]thia...)
Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(Cc2ccccc2)c2ccccc12 |t:3|
Show InChI InChI=1S/C23H17N3O4S/c27-21-16-10-4-6-12-18(16)26(14-15-8-2-1-3-9-15)23(28)20(21)22-24-17-11-5-7-13-19(17)31(29,30)25-22/h1-13,27H,14H2,(H,24,25)
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 82n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay

J Med Chem 49: 971-83 (2006)


Article DOI: 10.1021/jm050855s
BindingDB Entry DOI: 10.7270/Q2N29WJJ
More data for this
Ligand-Target Pair