null

SMILES: CCOC(=O)CNc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1

InChI Key: InChIKey=OGFBGXULTNAQFC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181608 (CHEMBL202310 | [3-(1,1-dioxo-1,4-dihydrobenzo[1,2,...) Show SMILES CCOC(=O)CNc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1 |t:20| Show InChI InChI=1S/C25H28N4O6S/c1-4-35-21(30)14-26-16-9-10-19-17(13-16)23(31)22(25(32)29(19)12-11-15(2)3)24-27-18-7-5-6-8-20(18)36(33,34)28-24/h5-10,13,15,26,31H,4,11-12,14H2,1-3H3,(H,27,28)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	265	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of HCV RNA replication in Huh7 cells				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50181608 (CHEMBL202310 | [3-(1,1-dioxo-1,4-dihydrobenzo[1,2,...) Show SMILES CCOC(=O)CNc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1 |t:20| Show InChI InChI=1S/C25H28N4O6S/c1-4-35-21(30)14-26-16-9-10-19-17(13-16)23(31)22(25(32)29(19)12-11-15(2)3)24-27-18-7-5-6-8-20(18)36(33,34)28-24/h5-10,13,15,26,31H,4,11-12,14H2,1-3H3,(H,27,28)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay				J Med Chem 49: 971-83 (2006) Article DOI: 10.1021/jm050855s BindingDB Entry DOI: 10.7270/Q2N29WJJ
					More data for this Ligand-Target Pair