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SMILES: CC(C)CCn1c2cccc(-c3ccccc3)c2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O

InChI Key: InChIKey=RNWNVAVOWHWAOH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181642   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181642
PNG
(3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-y...)
Show SMILES CC(C)CCn1c2cccc(-c3ccccc3)c2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O |t:23|
Show InChI InChI=1S/C27H25N3O4S/c1-17(2)15-16-30-21-13-8-11-19(18-9-4-3-5-10-18)23(21)25(31)24(27(30)32)26-28-20-12-6-7-14-22(20)35(33,34)29-26/h3-14,17,31H,15-16H2,1-2H3,(H,28,29)
UniProtKB/TrEMBL

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 144n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay

J Med Chem 49: 971-83 (2006)


Article DOI: 10.1021/jm050855s
BindingDB Entry DOI: 10.7270/Q2N29WJJ
More data for this
Ligand-Target Pair