BDBM50181946 2-(4-(4-(trifluoromethyl)benzyloxy)phenyl)-1-cyclopentyl-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL378157

SMILES: OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1

InChI Key: InChIKey=CARBPJFCDAHMQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181946 (2-(4-(4-(trifluoromethyl)benzyloxy)phenyl)-1-cyclo...) Show SMILES OC(=O)c1ccc2n(C3CCCC3)c(nc2c1)-c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C27H23F3N2O3/c28-27(29,30)20-10-5-17(6-11-20)16-35-22-12-7-18(8-13-22)25-31-23-15-19(26(33)34)9-14-24(23)32(25)21-3-1-2-4-21/h5-15,21H,1-4,16H2,(H,33,34)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 1859-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.032 BindingDB Entry DOI: 10.7270/Q2BK1BX6
					More data for this Ligand-Target Pair