BDBM50181952 2-[4-(biphenyl-2-yloxy)-phenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL379241

SMILES: OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(Oc2ccccc2-c2ccccc2)cc1

InChI Key: InChIKey=XWBMOABRLCSNSB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181952 (2-[4-(biphenyl-2-yloxy)-phenyl]-1-cyclohexyl-1H-be...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(Oc2ccccc2-c2ccccc2)cc1 Show InChI InChI=1S/C32H28N2O3/c35-32(36)24-17-20-29-28(21-24)33-31(34(29)25-11-5-2-6-12-25)23-15-18-26(19-16-23)37-30-14-8-7-13-27(30)22-9-3-1-4-10-22/h1,3-4,7-10,13-21,25H,2,5-6,11-12H2,(H,35,36)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against HCV 1b NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 1859-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.032 BindingDB Entry DOI: 10.7270/Q2BK1BX6
					More data for this Ligand-Target Pair