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SMILES: CC(C)CCN1[C@H](C(=O)C(C1=O)C1=Nc2ccccc2S(=O)(=O)N1)C(C)(C)C

InChI Key: InChIKey=RJSKUXAPHAJBFU-OMOCHNIRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181957   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181957
PNG
((S)-5-tert-butyl-3-(1,1-dioxo-1,4-dihydro-1-benzo[...)
Show SMILES CC(C)CCN1[C@H](C(=O)C(C1=O)C1=Nc2ccccc2S(=O)(=O)N1)C(C)(C)C |t:13|
Show InChI InChI=1S/C20H27N3O4S/c1-12(2)10-11-23-17(20(3,4)5)16(24)15(19(23)25)18-21-13-8-6-7-9-14(13)28(26,27)22-18/h6-9,12,15,17H,10-11H2,1-5H3,(H,21,22)/t15?,17-/m1/s1
UniProtKB/TrEMBL

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Article
PubMed
n/an/a 18n/an/an/an/an/an/a



GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of HCV NS5B RNA dependent RNA polymerase

Bioorg Med Chem Lett 16: 2205-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.034
BindingDB Entry DOI: 10.7270/Q26T0M6W
More data for this
Ligand-Target Pair