BindingDB logo
myBDB logout

null

SMILES: C1Oc2ccc(Nc3ncc4ccn(-c5ccccn5)c4n3)cc2O1

InChI Key: InChIKey=CFMISVIWAIFUAD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181971   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181971
PNG
(CHEMBL426673 | N-(benzo[d][1,3]dioxol-5-yl)-7-(pyr...)
Show SMILES C1Oc2ccc(Nc3ncc4ccn(-c5ccccn5)c4n3)cc2O1
Show InChI InChI=1S/C18H13N5O2/c1-2-7-19-16(3-1)23-8-6-12-10-20-18(22-17(12)23)21-13-4-5-14-15(9-13)25-11-24-14/h1-10H,11H2,(H,20,21,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair		3D
3D Structure (docked)