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SMILES: FC(F)(F)c1ccccc1Nc1ncc2ccn(-c3ccccn3)c2n1

InChI Key: InChIKey=NRQSTHBBOMUCMH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181973   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181973
PNG
(7-(pyridin-2-yl)-N-(2-(trifluoromethyl)phenyl)-7H-...)
Show SMILES FC(F)(F)c1ccccc1Nc1ncc2ccn(-c3ccccn3)c2n1
Show InChI InChI=1S/C18H12F3N5/c19-18(20,21)13-5-1-2-6-14(13)24-17-23-11-12-8-10-26(16(12)25-17)15-7-3-4-9-22-15/h1-11H,(H,23,24,25)
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MMDB

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Article
PubMed
n/an/a 7.00E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair