BindingDB logo
myBDB logout

null

SMILES: COc1ccc(C)c(Nc2ncc3ccn(-c4ccccn4)c3n2)c1

InChI Key: InChIKey=GFYSMCVIJGKQFK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181983   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181983
PNG
(CHEMBL377957 | N-(5-methoxy-2-methylphenyl)-7-(pyr...)
Show SMILES COc1ccc(C)c(Nc2ncc3ccn(-c4ccccn4)c3n2)c1
Show InChI InChI=1S/C19H17N5O/c1-13-6-7-15(25-2)11-16(13)22-19-21-12-14-8-10-24(18(14)23-19)17-5-3-4-9-20-17/h3-12H,1-2H3,(H,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair		3D
3D Structure (docked)