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SMILES: CCOC(=O)Cc1cnc(Nc2cc(OC)c(OC)c(OC)c2)nc1Nc1ccccn1

InChI Key: InChIKey=YHROPQPNDJZFTP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181987   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181987
PNG
(CHEMBL204933 | ethyl 2-(4-(pyridin-2-ylamino)-2-(3...)
Show SMILES CCOC(=O)Cc1cnc(Nc2cc(OC)c(OC)c(OC)c2)nc1Nc1ccccn1
Show InChI InChI=1S/C22H25N5O5/c1-5-32-19(28)10-14-13-24-22(27-21(14)26-18-8-6-7-9-23-18)25-15-11-16(29-2)20(31-4)17(12-15)30-3/h6-9,11-13H,5,10H2,1-4H3,(H2,23,24,25,26,27)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair