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SMILES: COc1cc(Nc2ncc3ccn(-c4nccc(Cl)n4)c3n2)cc(OC)c1OC

InChI Key: InChIKey=BNXZQALBAXHGOC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181992   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50181992
PNG
(7-(4-chloropyrimidin-2-yl)-N-(3,4,5-trimethoxyphen...)
Show SMILES COc1cc(Nc2ncc3ccn(-c4nccc(Cl)n4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C19H17ClN6O3/c1-27-13-8-12(9-14(28-2)16(13)29-3)23-18-22-10-11-5-7-26(17(11)25-18)19-21-6-4-15(20)24-19/h4-10H,1-3H3,(H,22,23,25)
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MMDB

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PC cid
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair