BindingDB logo
myBDB logout

null

SMILES: COc1cc(Nc2ncc3ccn(CCc4ccncc4)c3n2)cc(OC)c1OC

InChI Key: InChIKey=JVMIOYCBQMUOQD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182000   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50182000
PNG
(7-(2-(pyridin-4-yl)ethyl)-N-(3,4,5-trimethoxypheny...)
Show SMILES COc1cc(Nc2ncc3ccn(CCc4ccncc4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C22H23N5O3/c1-28-18-12-17(13-19(29-2)20(18)30-3)25-22-24-14-16-7-11-27(21(16)26-22)10-6-15-4-8-23-9-5-15/h4-5,7-9,11-14H,6,10H2,1-3H3,(H,24,25,26)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 7.50E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair