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SMILES: COc1cc(Nc2ncc3CCN(c3n2)c2ccccn2)cc(OC)c1OC

InChI Key: InChIKey=DCJLVDPCLZBHMK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182014   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50182014
PNG
(7-(pyridin-2-yl)-N-(3,4,5-trimethoxyphenyl)-6,7-di...)
Show SMILES COc1cc(Nc2ncc3CCN(c3n2)c2ccccn2)cc(OC)c1OC
Show InChI InChI=1S/C20H21N5O3/c1-26-15-10-14(11-16(27-2)18(15)28-3)23-20-22-12-13-7-9-25(19(13)24-20)17-6-4-5-8-21-17/h4-6,8,10-12H,7,9H2,1-3H3,(H,22,23,24)
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n/an/a 100n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibitory activity against FAK

Bioorg Med Chem Lett 16: 2173-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.053
BindingDB Entry DOI: 10.7270/Q2319VGX
More data for this
Ligand-Target Pair