BDBM50182078 CHEMBL382833::N-(4-diethylamino-1-methyl-butyl)-N'-{2-[2-(3,5-dimethoxy-phenyl)-ethyl]-3-fluoro-benzoyl}-guanidine
SMILES: CCN(CC)CCCC(C)N=C(N)NC(=O)c1cccc(F)c1CCc1cc(OC)cc(OC)c1
InChI Key: InChIKey=ZNAXZUPTUUWGDD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50182078 (CHEMBL382833 | N-(4-diethylamino-1-methyl-butyl)-N...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity to MC4R by membrane filtration assay | Bioorg Med Chem Lett 16: 2302-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.016 BindingDB Entry DOI: 10.7270/Q2PV6JZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanocortin receptor 4 (Homo sapiens (Human)) | BDBM50182078 (CHEMBL382833 | N-(4-diethylamino-1-methyl-butyl)-N...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Antagonist activity against MC4R by cAMP functional assay | Bioorg Med Chem Lett 16: 2302-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.016 BindingDB Entry DOI: 10.7270/Q2PV6JZW | |||||||||||
More data for this Ligand-Target Pair |