BDBM50182155 5-methylsulfanyl-4-(1-pyridin-2-ylmethyl-1H-benzoimidazole-5-sulfonyl)-thiophene-2-carboxamidine::CHEMBL382447

SMILES: CSc1sc(cc1S(=O)(=O)c1ccc2n(Cc3ccccn3)cnc2c1)C(N)=N

InChI Key: InChIKey=LWKXBZNNUAZNID-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50182155 (5-methylsulfanyl-4-(1-pyridin-2-ylmethyl-1H-benzoi...) Show SMILES CSc1sc(cc1S(=O)(=O)c1ccc2n(Cc3ccccn3)cnc2c1)C(N)=N Show InChI InChI=1S/C19H17N5O2S3/c1-27-19-17(9-16(28-19)18(20)21)29(25,26)13-5-6-15-14(8-13)23-11-24(15)10-12-4-2-3-7-22-12/h2-9,11H,10H2,1H3,(H3,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of C1S				Bioorg Med Chem Lett 16: 2200-4 (2006) Article DOI: 10.1016/j.bmcl.2006.01.036 BindingDB Entry DOI: 10.7270/Q2251HSV
					More data for this Ligand-Target Pair