BDBM50182260 CHEMBL3819013

SMILES: C[C@H]1CN(C[C@@H](C)O1)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O

InChI Key: InChIKey=OLLOVPYJXBHDTQ-PHIMTYICSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50182260 (CHEMBL3819013) Show SMILES C[C@H]1CN(C[C@@H](C)O1)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O |r| Show InChI InChI=1S/C19H20Cl2FN3O5S/c1-10-8-25(9-11(2)30-10)31(28,29)18-12(20)6-7-15(17(18)26)24-19(27)23-14-5-3-4-13(22)16(14)21/h3-7,10-11,26H,8-9H2,1-2H3,(H2,23,24,27)/t10-,11+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CXCR2 assessed as inhibition of CXCL1-induced neutrophil chemotaxis after 45 mins by calcein-AM dye based pl...				ACS Med Chem Lett 7: 397-402 (2016) BindingDB Entry DOI: 10.7270/Q2KW5HZH
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50182260 (CHEMBL3819013) Show SMILES C[C@H]1CN(C[C@@H](C)O1)S(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2cccc(F)c2Cl)c1O |r| Show InChI InChI=1S/C19H20Cl2FN3O5S/c1-10-8-25(9-11(2)30-10)31(28,29)18-12(20)6-7-15(17(18)26)24-19(27)23-14-5-3-4-13(22)16(14)21/h3-7,10-11,26H,8-9H2,1-2H3,(H2,23,24,27)/t10-,11+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Peking Union Medical College and Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Antagonist activity at human recombinant Gal4-VP16 fused-CXCR2 assessed as inhibition of CXCL1-mediated lactamase reporter gene expression after over...				ACS Med Chem Lett 7: 397-402 (2016) BindingDB Entry DOI: 10.7270/Q2KW5HZH
					More data for this Ligand-Target Pair