BDBM50182285 CHEMBL3819473
SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@@H](O)CC(O)(C(F)(F)F)C(F)(F)F
InChI Key: InChIKey=OHKBOEWLASAFLW-FJWDNACWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor 2 (Homo sapiens (Human)) | BDBM50182285 (CHEMBL3819473) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Inhibition of human recombinant FGF2 assessed as reduction in HSPG/FGF2/FGDR interaction by measuring FGF2 mediated A475-CHO-flg-1A-luc cell to CHO-K... | J Med Chem 59: 4651-63 (2016) BindingDB Entry DOI: 10.7270/Q26Q205Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor 2 (Homo sapiens (Human)) | BDBM50182285 (CHEMBL3819473) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Parma Curated by ChEMBL | Assay Description Binding affinity to human recombinant FGF2 treated for 4 mins measured after 10 mins by surface plasmon resonance spectroscopic analysis | J Med Chem 59: 4651-63 (2016) BindingDB Entry DOI: 10.7270/Q26Q205Q | |||||||||||
More data for this Ligand-Target Pair |