BDBM50182298 7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bicyclo[3.2.1]octan-3-yl)phenoxy)methyl)-4-phenyl-2H-chromen-2-one::CHEMBL204781

SMILES: O[C@]1(C[C@H]2CO[C@@H](C1)O2)c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccccc2)c1

InChI Key: InChIKey=MRUZHPQFENMWTJ-SUIMDOTNSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50182298   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50182298 (7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...) Show SMILES O[C@]1(C[C@H]2CO[C@@H](C1)O2)c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccccc2)c1 Show InChI InChI=1S/C28H23FO6/c29-20-9-19(28(31)13-22-16-33-27(14-28)34-22)10-21(11-20)32-15-17-6-7-23-24(18-4-2-1-3-5-18)12-26(30)35-25(23)8-17/h1-12,22,27,31H,13-16H2/t22?,27?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human 5-LO				Bioorg Med Chem Lett 16: 2528-31 (2006) Article DOI: 10.1016/j.bmcl.2006.01.085 BindingDB Entry DOI: 10.7270/Q2NV9HVZ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50182298 (7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...) Show SMILES O[C@]1(C[C@H]2CO[C@@H](C1)O2)c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccccc2)c1 Show InChI InChI=1S/C28H23FO6/c29-20-9-19(28(31)13-22-16-33-27(14-28)34-22)10-21(11-20)32-15-17-6-7-23-24(18-4-2-1-3-5-18)12-26(30)35-25(23)8-17/h1-12,22,27,31H,13-16H2/t22?,27?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of LTB4 production in calcium ionophore A-23187-stimulated human polymorphonuclear leukocyte				Bioorg Med Chem Lett 16: 2528-31 (2006) Article DOI: 10.1016/j.bmcl.2006.01.085 BindingDB Entry DOI: 10.7270/Q2NV9HVZ
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50182298 (7-((3-fluoro-5-((1S,3S,5R)-3-hydroxy-6,8-dioxa-bic...) Show SMILES O[C@]1(C[C@H]2CO[C@@H](C1)O2)c1cc(F)cc(OCc2ccc3c(cc(=O)oc3c2)-c2ccccc2)c1 Show InChI InChI=1S/C28H23FO6/c29-20-9-19(28(31)13-22-16-33-27(14-28)34-22)10-21(11-20)32-15-17-6-7-23-24(18-4-2-1-3-5-18)12-26(30)35-25(23)8-17/h1-12,22,27,31H,13-16H2/t22?,27?,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of LTB4 production in calcium ionophore A23187-stimulated human whole blood				Bioorg Med Chem Lett 16: 2528-31 (2006) Article DOI: 10.1016/j.bmcl.2006.01.085 BindingDB Entry DOI: 10.7270/Q2NV9HVZ
					More data for this Ligand-Target Pair