BDBM50182432 CHEMBL3818591
SMILES: Cc1ccccc1-c1cc(Nc2nccs2)ccc1C
InChI Key: InChIKey=OZBQQKIXAODXQL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LDL-associated phospholipase A2 (Homo sapiens (Human)) | BDBM50182432 (CHEMBL3818591) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Astex Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assay | J Med Chem 59: 5356-67 (2016) BindingDB Entry DOI: 10.7270/Q2Z60R0G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |