BDBM50182466 3'-(7-methyl-imidazo[1,2-b]pyridazin-3-yl)-biphenyl-2-carbonitrile::CHEMBL202070

SMILES: Cc1cnn2c(cnc2c1)-c1cccc(c1)-c1ccccc1C#N

InChI Key: InChIKey=VFZLFQOBMMOQQX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50182466 (3'-(7-methyl-imidazo[1,2-b]pyridazin-3-yl)-bipheny...) Show SMILES Cc1cnn2c(cnc2c1)-c1cccc(c1)-c1ccccc1C#N Show InChI InChI=1S/C20H14N4/c1-14-9-20-22-13-19(24(20)23-12-14)16-7-4-6-15(10-16)18-8-3-2-5-17(18)11-21/h2-10,12-13H,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABAA alpha1 receptor plus beta3gamma2 expressed in L(tk-) cells				J Med Chem 49: 1235-8 (2006) Article DOI: 10.1021/jm051200u BindingDB Entry DOI: 10.7270/Q2H41R04
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50182466 (3'-(7-methyl-imidazo[1,2-b]pyridazin-3-yl)-bipheny...) Show SMILES Cc1cnn2c(cnc2c1)-c1cccc(c1)-c1ccccc1C#N Show InChI InChI=1S/C20H14N4/c1-14-9-20-22-13-19(24(20)23-12-14)16-7-4-6-15(10-16)18-8-3-2-5-17(18)11-21/h2-10,12-13H,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H] Ro15-1788 from recombinant human GABAA alpha2 receptor plus beta3gamma2 expressed in L(tk-) cells				J Med Chem 49: 1235-8 (2006) Article DOI: 10.1021/jm051200u BindingDB Entry DOI: 10.7270/Q2H41R04
					More data for this Ligand-Target Pair