BDBM50182470 5,6,7-trimethoxy-1,2,3,8-tetrahydro-benzo[a]pyrrolo[3,4-c]-carbazol-1,3-dione::CHEMBL380898

SMILES: COc1cc2c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c2c(OC)c1OC

InChI Key: InChIKey=WMBYWABZHUPZDB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50182470 (5,6,7-trimethoxy-1,2,3,8-tetrahydro-benzo[a]pyrrol...) Show SMILES COc1cc2c3C(=O)NC(=O)c3c3c4ccccc4[nH]c3c2c(OC)c1OC Show InChI InChI=1S/C21H16N2O5/c1-26-12-8-10-14-16(21(25)23-20(14)24)13-9-6-4-5-7-11(9)22-17(13)15(10)19(28-3)18(12)27-2/h4-8,22H,1-3H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				J Med Chem 49: 1271-81 (2006) Article DOI: 10.1021/jm0580297 BindingDB Entry DOI: 10.7270/Q2CC108S
					More data for this Ligand-Target Pair