BDBM50182471 3-(indole-3-yl)-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2,5-dione::CHEMBL201264

SMILES: COc1ccc(cc1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12

InChI Key: InChIKey=XYZMTWPLQIFNDJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50182471 (3-(indole-3-yl)-4-(3,4-dimethoxyphenyl)-1H-pyrrole...) Show SMILES COc1ccc(cc1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccccc12 |t:11| Show InChI InChI=1S/C20H16N2O4/c1-25-15-8-7-11(9-16(15)26-2)17-18(20(24)22-19(17)23)13-10-21-14-6-4-3-5-12(13)14/h3-10,21H,1-2H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				J Med Chem 49: 1271-81 (2006) Article DOI: 10.1021/jm0580297 BindingDB Entry DOI: 10.7270/Q2CC108S
					More data for this Ligand-Target Pair