BDBM50182528 CHEMBL3818743::US9512121, 7

SMILES: [H][C@@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2

InChI Key: InChIKey=AVLLGHFOBOLCPF-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182528 (CHEMBL3818743 | US9512121, 7) Show SMILES [H][C@@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2 |r| Show InChI InChI=1S/C24H20FN7OS/c1-30-11-15(9-27-30)14-7-19(25)23-28-29-24(32(23)12-14)34-17-4-5-20-18(8-17)22-21(10-26-20)31-6-2-3-16(31)13-33-22/h4-5,7-12,16H,2-3,6,13H2,1H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysis				Bioorg Med Chem 24: 3483-93 (2016) BindingDB Entry DOI: 10.7270/Q29G5PQT
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182528 (CHEMBL3818743 | US9512121, 7) Show SMILES [H][C@@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2 |r| Show InChI InChI=1S/C24H20FN7OS/c1-30-11-15(9-27-30)14-7-19(25)23-28-29-24(32(23)12-14)34-17-4-5-20-18(8-17)22-21(10-26-20)31-6-2-3-16(31)13-33-22/h4-5,7-12,16H,2-3,6,13H2,1H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair