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BDBM50182558 CHEMBL3819608

SMILES: Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5N(CCOc5c4c3)C(=O)C3CC3)n2c1

InChI Key: InChIKey=ZRIJONWBCNFMEB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182558   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50182558
PNG
(CHEMBL3819608)
Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5N(CCOc5c4c3)C(=O)C3CC3)n2c1
Show InChI InChI=1S/C25H20FN7O2S/c1-31-12-16(10-28-31)15-8-19(26)23-29-30-25(33(23)13-15)36-17-4-5-20-18(9-17)22-21(11-27-20)32(6-7-35-22)24(34)14-2-3-14/h4-5,8-14H,2-3,6-7H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 43n/an/an/an/an/an/a



Southeast University

Curated by ChEMBL


Assay Description
Inhibition of c-Met (unknown origin) incubated for 1 hr by spectrophotometric analysis


Bioorg Med Chem 24: 3483-93 (2016)


BindingDB Entry DOI: 10.7270/Q29G5PQT
More data for this
Ligand-Target Pair