BDBM50182587 5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methoxybenzofuran::CHEMBL382154

SMILES: COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12

InChI Key: InChIKey=DPURAGOSIHFKPV-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.1 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.4 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.5 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv11.1 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of Kv1.2 channel				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.3 (Mus musculus)	BDBM50182587 (5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...) Show SMILES COc1c(O)c(C(C)=O)c(OCc2ccc(Cl)cc2)c2ccoc12 Show InChI InChI=1S/C18H15ClO5/c1-10(20)14-15(21)18(22-2)17-13(7-8-23-17)16(14)24-9-11-3-5-12(19)6-4-11/h3-8,21H,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Institute of Medical Research Biotechnology Centre Curated by ChEMBL					Assay Description Effect on blockade of mouse Kv1.3 channel expressed in L929 cells				J Med Chem 49: 1433-41 (2006) Article DOI: 10.1021/jm050839v BindingDB Entry DOI: 10.7270/Q2KW5FM6
					More data for this Ligand-Target Pair