BDBM50182661 3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-quinolyl)-4-piperazinyl]butyl}-6-anilinouracil::CHEMBL370868

SMILES: OC(=O)c1cn(C2CC2)c2cc(N3CCN(CCCCn4c(=O)cc(Nc5ccccc5)[nH]c4=O)CC3)c(F)cc2c1=O

InChI Key: InChIKey=BYVGRESTQAOAGC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase IIIC (Bacillus subtilis)	BDBM50182661 (3-{4-[1-(1-cyclopropyl-3-carboxy-4-oxo-6-fluoro-7-...) Show SMILES OC(=O)c1cn(C2CC2)c2cc(N3CCN(CCCCn4c(=O)cc(Nc5ccccc5)[nH]c4=O)CC3)c(F)cc2c1=O Show InChI InChI=1S/C31H33FN6O5/c32-24-16-22-25(38(21-8-9-21)19-23(29(22)40)30(41)42)17-26(24)36-14-12-35(13-15-36)10-4-5-11-37-28(39)18-27(34-31(37)43)33-20-6-2-1-3-7-20/h1-3,6-7,16-19,21,33H,4-5,8-15H2,(H,34,43)(H,41,42)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Binding affinity to Bacillus subtilis DNA polymerase3C				J Med Chem 49: 1455-65 (2006) Article DOI: 10.1021/jm0510023 BindingDB Entry DOI: 10.7270/Q23J3DR1
					More data for this Ligand-Target Pair