BDBM50182741 CHEMBL3818056

SMILES: Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1

InChI Key: InChIKey=WTLKEIKBWCDFDL-UHFFFAOYSA-N

Data: 13 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50182741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT7 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D3 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D3 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	358	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	366	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	773	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from rat D4 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
Dopamine receptor (RAT)	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	776	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from rat D4 receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50182741 (CHEMBL3818056) Show SMILES Oc1ccc(cc1)C(=O)CCCN1CCc2ccccc2C1 Show InChI InChI=1S/C19H21NO2/c21-18-9-7-16(8-10-18)19(22)6-3-12-20-13-11-15-4-1-2-5-17(15)14-20/h1-2,4-5,7-10,21H,3,6,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	851	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Florida A&M University Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in cell membranes after 1 hr by liquid scintillation counting				Bioorg Med Chem 24: 3464-71 (2016) BindingDB Entry DOI: 10.7270/Q2X63PVP
					More data for this Ligand-Target Pair