BDBM50182795 5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl)hexyl)naphthalene-1-sulfonamide::CHEMBL205982
SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCN1C[C@H](O)[C@@H](O)[C@@H](O)[C@H]1CO
InChI Key: InChIKey=ZGRFZJIZQMHGFV-AWAHEQQVSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
beta-Galactosidase (β-gal) (Escherichia coli (Enterobacteria)) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of human lysosomal beta-galactosidase assessed as inhibition of hydrolyzed 4-methylumbelliferone production after 30 mins by luminescence ... | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Rhizobium meliloti) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität Graz Curated by ChEMBL | Assay Description Inhibition of Agrobacterium sp. beta-galactosidase | Bioorg Med Chem Lett 16: 2067-70 (2006) Article DOI: 10.1016/j.bmcl.2006.01.095 BindingDB Entry DOI: 10.7270/Q26Q1WV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
α-galactosidase (Coffea arabica (Coffee beans)) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of green coffee bean alpha-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair |