BDBM50183131 CHEMBL208232::N-(2-fluoro-4-(trifluoromethyl)benzyl)-N-isobutylpiperidin-4-amine fumaric acid salt

SMILES: CC(C)CN(Cc1ccc(cc1F)C(F)(F)F)C1CCNCC1

InChI Key: InChIKey=RYBKAECQSIBTTL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50183131 (CHEMBL208232 | N-(2-fluoro-4-(trifluoromethyl)benz...) Show SMILES CC(C)CN(Cc1ccc(cc1F)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C17H24F4N2/c1-12(2)10-23(15-5-7-22-8-6-15)11-13-3-4-14(9-16(13)18)17(19,20)21/h3-4,9,12,15,22H,5-8,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50183131 (CHEMBL208232 | N-(2-fluoro-4-(trifluoromethyl)benz...) Show SMILES CC(C)CN(Cc1ccc(cc1F)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C17H24F4N2/c1-12(2)10-23(15-5-7-22-8-6-15)11-13-3-4-14(9-16(13)18)17(19,20)21/h3-4,9,12,15,22H,5-8,10-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50183131 (CHEMBL208232 | N-(2-fluoro-4-(trifluoromethyl)benz...) Show SMILES CC(C)CN(Cc1ccc(cc1F)C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C17H24F4N2/c1-12(2)10-23(15-5-7-22-8-6-15)11-13-3-4-14(9-16(13)18)17(19,20)21/h3-4,9,12,15,22H,5-8,10-11H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]WIN35 from DAT				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair