BDBM50183153 CHEMBL382248::N-(2-(trifluoromethyl)benzyl)-N-(2-methoxyethyl)piperidin-4-amine fumaric acid salt

SMILES: COCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1

InChI Key: InChIKey=SMIBSYJYIPYGBA-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50183153 (CHEMBL382248 | N-(2-(trifluoromethyl)benzyl)-N-(2-...) Show SMILES COCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C16H23F3N2O/c1-22-11-10-21(14-6-8-20-9-7-14)12-13-4-2-3-5-15(13)16(17,18)19/h2-5,14,20H,6-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50183153 (CHEMBL382248 | N-(2-(trifluoromethyl)benzyl)-N-(2-...) Show SMILES COCCN(Cc1ccccc1C(F)(F)F)C1CCNCC1 Show InChI InChI=1S/C16H23F3N2O/c1-22-11-10-21(14-6-8-20-9-7-14)12-13-4-2-3-5-15(13)16(17,18)19/h2-5,14,20H,6-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair