BDBM50183170 CHEMBL207480::N-(4-fluoro-2-(trifluoromethyl)benzyl)-N-(cyclobutylmethyl)piperidin-4-amine tartaric acid salt

SMILES: Fc1ccc(CN(CC2CCC2)C2CCNCC2)c(c1)C(F)(F)F

InChI Key: InChIKey=VVKADMNJXPXHTR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50183170 (CHEMBL207480 | N-(4-fluoro-2-(trifluoromethyl)benz...) Show SMILES Fc1ccc(CN(CC2CCC2)C2CCNCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C18H24F4N2/c19-15-5-4-14(17(10-15)18(20,21)22)12-24(11-13-2-1-3-13)16-6-8-23-9-7-16/h4-5,10,13,16,23H,1-3,6-9,11-12H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50183170 (CHEMBL207480 | N-(4-fluoro-2-(trifluoromethyl)benz...) Show SMILES Fc1ccc(CN(CC2CCC2)C2CCNCC2)c(c1)C(F)(F)F Show InChI InChI=1S/C18H24F4N2/c19-15-5-4-14(17(10-15)18(20,21)22)12-24(11-13-2-1-3-13)16-6-8-23-9-7-16/h4-5,10,13,16,23H,1-3,6-9,11-12H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from NET				Bioorg Med Chem Lett 16: 2714-8 (2006) Article DOI: 10.1016/j.bmcl.2006.02.008 BindingDB Entry DOI: 10.7270/Q2SF2VR6
					More data for this Ligand-Target Pair