BDBM50183203 CHEMBL208008::N-(4-sulfamoyl-phenyl)-2-[1-(2,4,6-trimethyl-phenyl)-1H-tetrazol-5-ylsulfanyl]-acetamide

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=XSLXWOXOADEZOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50183203 (CHEMBL208008 | N-(4-sulfamoyl-phenyl)-2-[1-(2,4,6-...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1)S(N)(=O)=O |(13.95,-2.13,;14.28,-.63,;13.14,.41,;13.47,1.92,;12.34,2.96,;14.94,2.39,;16.08,1.35,;17.54,1.82,;15.75,-.16,;15.26,3.89,;14.24,5.05,;15.01,6.38,;16.52,6.05,;16.67,4.52,;18,3.75,;19.34,4.51,;20.67,3.74,;20.67,2.2,;22.01,4.51,;23.34,3.74,;23.33,2.2,;24.66,1.42,;26,2.19,;26,3.74,;24.66,4.5,;27.33,1.42,;28.66,.65,;26.56,.09,;28.11,2.75,)| Show InChI InChI=1S/C18H20N6O3S2/c1-11-8-12(2)17(13(3)9-11)24-18(21-22-23-24)28-10-16(25)20-14-4-6-15(7-5-14)29(19,26)27/h4-9H,10H2,1-3H3,(H,20,25)(H2,19,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair