BDBM50183207 CHEMBL377010::N-(2-chlorophenyl)-2-(1-mesityl-1H-tetrazol-5-ylthio)acetamide
SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccccc1Cl
InChI Key: InChIKey=IZTWDVIZDRDIQB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50183207 (CHEMBL377010 | N-(2-chlorophenyl)-2-(1-mesityl-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
MRL Rome Curated by ChEMBL | Assay Description Inhibition of HIV1 wild type Reverse Transcriptase | Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50183207 (CHEMBL377010 | N-(2-chlorophenyl)-2-(1-mesityl-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of wild type HIV1 reverse transcriptase | Bioorg Med Chem 17: 6374-9 (2009) Article DOI: 10.1016/j.bmc.2009.07.027 BindingDB Entry DOI: 10.7270/Q2VQ35G3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50183207 (CHEMBL377010 | N-(2-chlorophenyl)-2-(1-mesityl-1H-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of polymerase activity of HIV1 RT | Bioorg Med Chem Lett 18: 5368-71 (2008) Article DOI: 10.1016/j.bmcl.2008.09.055 BindingDB Entry DOI: 10.7270/Q2FB55RX | |||||||||||
More data for this Ligand-Target Pair |