BDBM50183213 2-(1-(2-chloro-5-fluorophenyl)-1H-tetrazol-5-ylthio)-N-(2-nitrophenyl)acetamide::CHEMBL205764
SMILES: [O-][N+](=O)c1ccccc1NC(=O)CSc1nnnn1-c1cc(F)ccc1Cl
InChI Key: InChIKey=JVEOTAZTQCLXGS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50183213 (2-(1-(2-chloro-5-fluorophenyl)-1H-tetrazol-5-ylthi...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
MRL Rome Curated by ChEMBL | Assay Description Inhibition of HIV1 wild type Reverse Transcriptase | Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R | |||||||||||
More data for this Ligand-Target Pair |