BDBM50183214 CHEMBL205094::N-(2,6-dichlorophenyl)-2-(1-mesityl-1H-tetrazol-5-ylthio)acetamide

SMILES: Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1c(Cl)cccc1Cl

InChI Key: InChIKey=JTUUTKLXAMMFKP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50183214 (CHEMBL205094 | N-(2,6-dichlorophenyl)-2-(1-mesityl...) Show SMILES Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1c(Cl)cccc1Cl |(15.42,-36.3,;15.76,-34.8,;14.62,-33.76,;14.95,-32.25,;13.81,-31.21,;16.42,-31.78,;17.56,-32.82,;19.02,-32.34,;17.23,-34.33,;16.74,-30.28,;15.71,-29.12,;16.49,-27.79,;17.99,-28.12,;18.15,-29.65,;19.48,-30.42,;20.82,-29.65,;22.15,-30.43,;22.15,-31.97,;23.48,-29.66,;24.82,-30.43,;26.14,-29.66,;26.14,-28.12,;27.47,-30.43,;27.48,-31.98,;26.14,-32.74,;24.81,-31.97,;23.47,-32.74,)| Show InChI InChI=1S/C18H17Cl2N5OS/c1-10-7-11(2)17(12(3)8-10)25-18(22-23-24-25)27-9-15(26)21-16-13(19)5-4-6-14(16)20/h4-8H,9H2,1-3H3,(H,21,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MRL Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type Reverse Transcriptase				Bioorg Med Chem Lett 16: 2748-52 (2006) Article DOI: 10.1016/j.bmcl.2006.02.024 BindingDB Entry DOI: 10.7270/Q2D79B1R
					More data for this Ligand-Target Pair