BDBM50183222 (S)-6-(3-isopropoxy-5-(1-phenylpropan-2-yloxy)benzamido)nicotinic acid::CHEMBL205816

SMILES: CC(C)Oc1cc(O[C@@H](C)Cc2ccccc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O

InChI Key: InChIKey=CLRXIUJLHYPICH-KRWDZBQOSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50183222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50183222 ((S)-6-(3-isopropoxy-5-(1-phenylpropan-2-yloxy)benz...) Show SMILES CC(C)Oc1cc(O[C@@H](C)Cc2ccccc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O Show InChI InChI=1S/C25H26N2O5/c1-16(2)31-21-12-20(24(28)27-23-10-9-19(15-26-23)25(29)30)13-22(14-21)32-17(3)11-18-7-5-4-6-8-18/h4-10,12-17H,11H2,1-3H3,(H,29,30)(H,26,27,28)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Activation of His-tagged recombinant glucokinase expressed in Escherichia coli using [14C]-glucose substrate by spectrophotometrically				Bioorg Med Chem Lett 21: 3467-70 (2011) Article DOI: 10.1016/j.bmcl.2011.03.093 BindingDB Entry DOI: 10.7270/Q2Z038HG
					More data for this Ligand-Target Pair
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50183222 ((S)-6-(3-isopropoxy-5-(1-phenylpropan-2-yloxy)benz...) Show SMILES CC(C)Oc1cc(O[C@@H](C)Cc2ccccc2)cc(c1)C(=O)Nc1ccc(cn1)C(O)=O Show InChI InChI=1S/C25H26N2O5/c1-16(2)31-21-12-20(24(28)27-23-10-9-19(15-26-23)25(29)30)13-22(14-21)32-17(3)11-18-7-5-4-6-8-18/h4-10,12-17H,11H2,1-3H3,(H,29,30)(H,26,27,28)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Activitation of glucokinase				Bioorg Med Chem Lett 16: 2705-9 (2006) Article DOI: 10.1016/j.bmcl.2006.02.022 BindingDB Entry DOI: 10.7270/Q28G8K91
					More data for this Ligand-Target Pair