BDBM50183244 3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-chromen-4-one::CHEMBL204948::[3,4''']biflavone

SMILES: O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1

InChI Key: InChIKey=DKAAIRCEBVCHAT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50183244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50183244 (3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned cPLA2 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Phospholipase A2 group 1B (Rattus norvegicus)	BDBM50183244 (3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Group X secretory phospholipase A2 (Homo sapiens (Human))	BDBM50183244 (3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Yeungnam University Curated by ChEMBL					Assay Description Inhibition of human cloned sPLA2-10 expressed in HEK293 cells				Bioorg Med Chem 15: 7138-43 (2007) Article DOI: 10.1016/j.bmc.2007.07.054 BindingDB Entry DOI: 10.7270/Q2WM1D5G
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50183244 (3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...) Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kangwon National University Curated by ChEMBL					Assay Description Inhibition of sPLA2-2A in HEK293 cell				Bioorg Med Chem Lett 16: 2373-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.117 BindingDB Entry DOI: 10.7270/Q20Z72VZ
					More data for this Ligand-Target Pair