BDBM50183969 4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-ylamino)-6-chloroquinolin-2(1H)-one::CHEMBL208028
SMILES: Clc1ccc2[nH]c(=O)cc(NC3CCN(Cc4ccc5OCOc5c4)CC3)c2c1
InChI Key: InChIKey=SNBBROUTMGTRAU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50183969 (4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Binding affinity to hERG stably transfected in HEK293 cells | Bioorg Med Chem Lett 16: 2621-7 (2006) Article DOI: 10.1016/j.bmcl.2006.02.044 BindingDB Entry DOI: 10.7270/Q2SB45CQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50183969 (4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells | Bioorg Med Chem Lett 16: 2621-7 (2006) Article DOI: 10.1016/j.bmcl.2006.02.044 BindingDB Entry DOI: 10.7270/Q2SB45CQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50183969 (4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of MCH-mediated calcium release in whole IMR32 cells by FLIPR | Bioorg Med Chem Lett 16: 2621-7 (2006) Article DOI: 10.1016/j.bmcl.2006.02.044 BindingDB Entry DOI: 10.7270/Q2SB45CQ | |||||||||||
More data for this Ligand-Target Pair |