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SMILES: COC(=O)CNC(=O)Cc1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12

InChI Key: InChIKey=NSXBBJOTAIVZJR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183976   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50183976
PNG
(CHEMBL207232 | methyl 2-(2-(3-(2-(3,4,5-trimethoxy...)
Show SMILES COC(=O)CNC(=O)Cc1cccc(c1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12
Show InChI InChI=1S/C26H27N5O6/c1-34-20-12-18(13-21(35-2)24(20)37-4)29-26-28-14-17-8-9-31(25(17)30-26)19-7-5-6-16(10-19)11-22(32)27-15-23(33)36-3/h5-10,12-14H,11,15H2,1-4H3,(H,27,32)(H,28,29,30)
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n/an/a 635n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair