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SMILES: COc1cc(Nc2ncc3ccn(-c4cccc(CN)c4)c3n2)cc(OC)c1OC

InChI Key: InChIKey=GEGKOCNSNRWFTA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50183982   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50183982
PNG
(7-(3-(aminomethyl)phenyl)-N-(3,4,5-trimethoxypheny...)
Show SMILES COc1cc(Nc2ncc3ccn(-c4cccc(CN)c4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C22H23N5O3/c1-28-18-10-16(11-19(29-2)20(18)30-3)25-22-24-13-15-7-8-27(21(15)26-22)17-6-4-5-14(9-17)12-23/h4-11,13H,12,23H2,1-3H3,(H,24,25,26)
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Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair