BDBM50184009 CHEMBL205584::N-methyl-6-(2-(3,4,5-trimethoxyphenylamino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)picolinamide

SMILES: CNC(=O)c1cccc(n1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12

InChI Key: InChIKey=CFVFPPBLSQGGFD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50184009 (CHEMBL205584 | N-methyl-6-(2-(3,4,5-trimethoxyphen...) Show SMILES CNC(=O)c1cccc(n1)-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc12 Show InChI InChI=1S/C22H22N6O4/c1-23-21(29)15-6-5-7-18(26-15)28-9-8-13-12-24-22(27-20(13)28)25-14-10-16(30-2)19(32-4)17(11-14)31-3/h5-12H,1-4H3,(H,23,29)(H,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation (GNF) Curated by ChEMBL					Assay Description Inhibition of FAK				Bioorg Med Chem Lett 16: 2689-92 (2006) Article DOI: 10.1016/j.bmcl.2006.02.032 BindingDB Entry DOI: 10.7270/Q2NK3DN0
					More data for this Ligand-Target Pair				3D Structure (docked)