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SMILES: COc1cc(Nc2ncc3ccn(-c4cccc(c4)C(=O)NC4CCCC4)c3n2)cc(OC)c1OC

InChI Key: InChIKey=UBCISQZHXMDWEY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184010   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Focal adhesion kinase 1


(Homo sapiens (Human))		BDBM50184010
PNG
(CHEMBL206978 | N-cyclopentyl-3-(2-(3,4,5-trimethox...)
Show SMILES COc1cc(Nc2ncc3ccn(-c4cccc(c4)C(=O)NC4CCCC4)c3n2)cc(OC)c1OC
Show InChI InChI=1S/C27H29N5O4/c1-34-22-14-20(15-23(35-2)24(22)36-3)30-27-28-16-18-11-12-32(25(18)31-27)21-10-6-7-17(13-21)26(33)29-19-8-4-5-9-19/h6-7,10-16,19H,4-5,8-9H2,1-3H3,(H,29,33)(H,28,30,31)
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Article
PubMed
n/an/a 4.11E+3n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation (GNF)

Curated by ChEMBL


Assay Description
Inhibition of FAK

Bioorg Med Chem Lett 16: 2689-92 (2006)


Article DOI: 10.1016/j.bmcl.2006.02.032
BindingDB Entry DOI: 10.7270/Q2NK3DN0
More data for this
Ligand-Target Pair